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KMID : 0364019770100020299
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Korean Journal of Thoracic and Cardiovascular Surgery
1977 Volume.10 No. 2 p.299 ~ p.314
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Clinical Experience of Open Heart Surgery under the Extracorporeal Circulation with Partial Hemodilution
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柳會性/Yoo, Hoe Sung
柳英善/李正浩/김주이/姜政豪/張雲夏/李弘燮/Yoo, Young Sun/Lee, Jung Ho/Kim, Ju E/Kang, Jung Ho/Chang, Un Ha/Lee, Hong Sup
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Abstract
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Clinical experience on 16 cases of open heart surgery under the extracorporeal circulation with mild or moderate hypothermia and partial hemodilution technique at the National Medical Center during the period from June 1976 to October 1977. Nine of sixteen were congenital heart disease and seven were acquired heart disease. The age of the patient ranged between 6 and 48 years.
The body weight varied from 18.5㎏ to 60㎏ and body surface area 0.79-1.70㎡. The average priming volume of pump oxygreator was 2080㎖, which was consisted fresh ACD blood, buffered Hartmann´s solution, Mannitol, 50% dextrose in water and Vit. C. The average hemodilution rate was 27%.
The average flow 2.3L/min/㎡ or 80㎖/min and the duration of perfusion varied from 31 min to 270 min with average of 107 min.
The perfusion was carried out under the mild or moderate hypothermia using core cooling alone in 10 cases, core cooling and local myocardial cooling with 0-4℃ physiologic saline in 2 cases.
From a hemodynamic point of view, the blood pressure dropped down around 80mmHg after the initiation of perfusion followed by increase to safety level and stable during the perfusion. The central venous pressure remained within normal limits. In most cases, Hemoglobin and hematocrit decreased during and after the perfusion. Hemoglobin level was decreased, average of 20.6%, hematocrit 18.6%, pletelets 55% postoperatively. Plasma hemoglobin increased moderately, from preperfusion average value of 7.79㎎% to post-perfusion value of 54.7㎎%.
Electrolytes changes during cardiopulmonary bypass showed definite hypokalemia but changes of Na, Ca were not definite.
Arterial blood gas analysis during cardiopulmonary bypass suggested that the metabolic acidosis which was accompanied by respirory alkalosis which was corrected postoperatively. As the operative complication, transient hemoglobinuria in cases and neurological signs in 2 cases were all cured.
There were 2 death cases and operative mortality rate was 12.5%.
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